AZothBio

Discovery Solution Provider

We provide a fast and efficient solution to facilitate novel drug discovery.
Our in-house biochemistry laboratories prove and ensure timely and consistent results.

Pipelines by MoliSTA

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Pipeline PDF Indication Status Brief MOA

AZBF11509

TYK2 Inhibitor

PDF다운

Autoimmune Disease

Fast Follower

Selective inhibition on JH2 domain of TYK2

AZBT12128

TRK Inhibitor

PDF다운

NTRK Gene Fusion Cancer

First-in-Class

Selective inhibition on TRK A

As of 2022.Q2

Pipeline Schedule

Pipeline 2021 2022 2023 2024
1Q 2Q 3Q 4Q 1Q 2Q 3Q 4Q 1Q 2Q 3Q 4Q 1Q 2Q 3Q 4Q
AZBF11509

Target analysis

In vitro

In vivo

Pre-clinical

License out

AZBT12128

Target analysis

In vitro

In vivo

Pre-clinical

License out

MoliSTA Based Solution

- From Hit Discovery to Lead Optimization

In silico

  • Step 1
    Virtual HTS
    Phenotype Based Screening
    On Target Activity
    Off Target Activity
  • Step 2
    Overall Analysis & Scoring
    3D Structure
    Toxicity & Adverse Effects
    Generating New Molecules
    Overall score

In vitro & In vivo

  • Step 3
    POC Verification
    In-House Lab Assay
    CRO & Research Partners
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